Disorders of eyelid, lacrimal system and orbit

H7_LIDLACRIMALORBIT

lacrimal apparatus disease: A non-neoplastic or neoplastic disorder that affects the lacrimal apparatus. [ NCIT:C26809 ]

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 H00-H06
Cause of death: ICD-10 H00-H06

24192

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

24192

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Check minimum number of events None

24192

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H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 24125 15721 8404
Unadjusted prevalence (%) 7.82 9.06 6.22
Mean age at first event (years) 56.92 55.29 59.99

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.51 [1.24, 1.84] 4.8e-5 1819
15 years 0.01 0.97 [0.82, 1.14] 6.9e-1 885
5 years 0.00 2.01 [1.75, 2.30] 3.8e-24 601
1 year 0.00 2.52 [2.06, 3.09] 3.0e-19 147

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_LIDLACRIMALORBIT – Disorders of eyelid, lacrimal system and orbit
GWS hits: 2

Survival analyses between endpoints

Plot

before Disorders of eyelid, lacrimal system and orbit
after Disorders of eyelid, lacrimal system and orbit

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Drugs most likely to be purchased after Disorders of eyelid, lacrimal system and orbit