Disorders of eyelid, lacrimal system and orbit

H7_LIDLACRIMALORBIT

lacrimal apparatus disease: A non-neoplastic or neoplastic disorder that affects the lacrimal apparatus. [ NCIT:C26809 ]

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H00-H06

Cause of death: ICD-10 H00-H06

24192

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

24192

Check minimum number of events None

24192

Include endpoints

H7_HORDEOLUM

H7_CHALAZION

H7_EYELIDINFLAMMATION

H7_EYELIDDIS

H7_LACRIMALSYSTEM

H7_ORBIT

24943

H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Disorders of eyelid, lacrimal system and orbit based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	24125	15721	8404
Unadjusted prevalence (%)	7.82	9.06	6.22
Mean age at first event (years)	56.92	55.29	59.99

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.51 [1.24, 1.84]	4.8e-5	1819
15 years	0.01	0.97 [0.82, 1.14]	6.9e-1	885
5 years	0.00	2.01 [1.75, 2.30]	3.8e-24	601
1 year	0.00	2.52 [2.06, 3.09]	3.0e-19	147

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_LIDLACRIMALORBIT – Disorders of eyelid, lacrimal system and orbit
GWS hits: 2

Survival analyses between endpoints

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Plot

before Disorders of eyelid, lacrimal system and orbit
after Disorders of eyelid, lacrimal system and orbit

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Table

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Drugs most likely to be purchased after Disorders of eyelid, lacrimal system and orbit

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