Disorders of lacrimal system

H7_LACRIMALSYSTEM

lacrimal apparatus disease: A non-neoplastic or neoplastic disorder that affects the lacrimal apparatus. [ NCIT:C26809 ]

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H04

Cause of death: ICD-10 H04

9713

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

9713

Check minimum number of events None

9713

Include endpoints

H7_DACRYOADENITIS

H7_LACRIGLAND

H7_EPIPHORA

H7_LACRIMINFLAMACU

H7_LACRIMINFLAMCHRON

H7_STENOLACRI

H7_LACRIPAS

H7_LACRINAS

10036

H7_LACRIMALSYSTEM

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H00-H06

Name in latin Morbositates apparati lacrimalis

Similar endpoints

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List of similar endpoints to Disorders of lacrimal system based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	9665	6964	2701
Unadjusted prevalence (%)	3.13	4.01	2.00
Mean age at first event (years)	55.50	54.42	58.29

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.55 [1.16, 2.07]	3.3e-3	575
15 years	0.01	0.90 [0.68, 1.21]	5.0e-1	272
5 years	0.00	2.00 [1.56, 2.56]	5.1e-8	201
1 year	0.00	2.70 [1.92, 3.81]	1.2e-8	51

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_LACRIMALSYSTEM – Disorders of lacrimal system
GWS hits: 0

Survival analyses between endpoints

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Plot

before Disorders of lacrimal system
after Disorders of lacrimal system

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Drugs most likely to be purchased after Disorders of lacrimal system

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