Generalized epilepsy, strict definition

GE_STRICT

generalised epilepsy: A chronic condition characterised by recurrent generalised seizures.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions

not FE

319960

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

GE

2273

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GE_STRICT

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 2197 1114 1083
Unadjusted prevalence (%) 0.71 0.64 0.80
Mean age at first event (years) 43.87 41.03 46.81

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 4.14 [2.70, 6.34] 6.3e-11 368
15 years 0.01 2.04 [1.42, 2.95] 1.3e-4 120
5 years 0.01 6.39 [4.82, 8.47] 5.5e-38 123
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: GE_STRICT – Generalized epilepsy, strict definition
GWS hits: 0

Survival analyses between endpoints

Plot

before Generalized epilepsy, strict definition
after Generalized epilepsy, strict definition

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Drugs most likely to be purchased after Generalized epilepsy, strict definition