Focal epilepsy, mode (most common among epilepsy diagnosis)

FE_MODE

partial epilepsy: A seizure caused by a localized disorder.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 G40.3
Hospital discharge: ICD-9 %345[4-5]
Hospital discharge: ICD-8 %3453
Cause of death: ICD-10 G40.3
Cause of death: ICD-9 %345[4-5]
Cause of death: ICD-8 %3453

8151

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Check pre-conditions, main-only, mode, ICD version

Check mode of ICD-10 codes: %3453, %345[4-5], %G403
Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1048

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Check minimum number of events None

1048

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Include endpoints None

1048

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FE_MODE

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 1297 773 524
Unadjusted prevalence (%) 0.42 0.45 0.39
Mean age at first event (years) 29.14 27.51 31.53

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.24 [1.22, 4.11] 8.9e-3 134
15 years 0.01 1.75 [1.07, 2.87] 2.5e-2 68
5 years 0.00 1.99 [1.21, 3.29] 7.1e-3 22
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: FE_MODE – Focal epilepsy, mode (most common among epilepsy diagnosis)
GWS hits: 0

Survival analyses between endpoints

Plot

before Focal epilepsy, mode (most common among epilepsy diagnosis)
after Focal epilepsy, mode (most common among epilepsy diagnosis)

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Drugs most likely to be purchased after Focal epilepsy, mode (most common among epilepsy diagnosis)