Focal epilepsy

DOID EFO MESH SNOMED PheWeb

partial epilepsy: A seizure caused by a localized disorder.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 G40.3

Hospital discharge: ICD-9 345[4-5]

Hospital discharge: ICD-8 3453

Cause of death: ICD-10 G40.3

Cause of death: ICD-9 345[4-5]

Cause of death: ICD-8 3453

1369

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1342

Check minimum number of events None

1342

Include endpoints None

1342

Extra metadata

First used in FinnGen datafreeze DF3

Parent code in ICD-10 G40

Similar endpoints

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List of similar endpoints to Focal epilepsy based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1297	773	524
Unadjusted prevalence (%)	0.42	0.45	0.39
Mean age at first event (years)	29.14	27.51	31.53

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.41 [0.63, 3.16]	4.1e-1	134
15 years	0.01	1.22 [0.61, 2.45]	5.8e-1	68
5 years	0.00	1.57 [0.84, 2.93]	1.5e-1	22
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: FE – Focal epilepsy
GWS hits: 0

Survival analyses between endpoints

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Plot

before Focal epilepsy
after Focal epilepsy

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Table

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Drugs most likely to be purchased after Focal epilepsy

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