Schizophrenia, schizotypal and delusional disorders

F5_SCHIZO

schizophrenia: A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality.

Endpoint definition

↥

FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 F20

Cause of death: ICD-10 F20

5748

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

5748

Check minimum number of events None

5748

Include endpoints

F5_SCHZPHR

F5_SCHIZOTYP

F5_DELUSIO

F5_PSYTRANS

F5_INDUDEL

F5_SCHIZOAFF

F5_PSYCHOTH

12187

F5_SCHIZO

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Parent code in ICD-10 F20-F29

Name in latin Schizophrenia

Similar endpoints

↥

List of similar endpoints to Schizophrenia, schizotypal and delusional disorders based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	11658	6032	5626
Unadjusted prevalence (%)	3.78	3.48	4.17
Mean age at first event (years)	34.47	35.60	33.25

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.71 [2.11, 3.47]	5.7e-15	889
15 years	0.01	1.75 [1.41, 2.17]	3.6e-7	368
5 years	0.00	3.01 [2.47, 3.67]	1.0e-27	180
1 year	0.00	5.58 [4.21, 7.41]	9.9e-33	66

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: F5_SCHIZO – Schizophrenia, schizotypal and delusional disorders
GWS hits: 1

Survival analyses between endpoints

↥

Plot

before Schizophrenia, schizotypal and delusional disorders
after Schizophrenia, schizotypal and delusional disorders

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Schizophrenia, schizotypal and delusional disorders

↥