Acute and transient psychotic disorders

F5_PSYTRANS

psychosis: An abnormal condition of the mind that involves a loss of contact with reality. People experiencing psychosis may exhibit personality changes and thought disorder. Depending on its severity, this may be accompanied by unusual or bizarre behavior, as well as difficulty with social interaction and impairment in carrying out daily life activities.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 F23
Hospital discharge: ICD-9 298
Hospital discharge: ICD-8 298
Hospital discharge: excluded ICD-8 2989
Cause of death: ICD-10 F23
Cause of death: ICD-9 298
Cause of death: ICD-8 298
Cause of death: excluded ICD-8 2989

4061

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

3958

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Check minimum number of events None

3958

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Include endpoints None

3958

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F5_PSYTRANS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F20-F29
Name in latin Perturbationes psychoticae acutae et temporariae

Summary Statistics

Key figures

All Female Male
Number of individuals 3789 2085 1704
Unadjusted prevalence (%) 1.23 1.20 1.26
Mean age at first event (years) 33.79 34.71 32.67

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.23 [1.49, 3.33] 9.0e-5 237
15 years 0.01 1.36 [0.93, 1.98] 1.1e-1 87
5 years 0.00 2.19 [1.46, 3.29] 1.6e-4 35
1 year 0.00 7.09 [4.35, 11.58] 4.4e-15 22

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: F5_PSYTRANS – Acute and transient psychotic disorders
GWS hits: 0

Survival analyses between endpoints

Plot

before Acute and transient psychotic disorders
after Acute and transient psychotic disorders

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Drugs most likely to be purchased after Acute and transient psychotic disorders