Schizophrenia

F5_SCHZPHR

schizophrenia: A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality.

Endpoint definition

↥

FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 F20

Hospital discharge: ICD-9 295

Hospital discharge: ICD-8 295

Hospital discharge: excluded ICD-9 2954|2957

Hospital discharge: excluded ICD-8 2957

Cause of death: ICD-10 F20

Cause of death: ICD-9 295

Cause of death: ICD-8 295

Cause of death: excluded ICD-9 2954|2957

Cause of death: excluded ICD-8 2957

6351

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

6287

Check minimum number of events None

6287

Include endpoints None

6287

F5_SCHZPHR

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 F20-F29

Name in latin Schizophrenia

Similar endpoints

↥

List of similar endpoints to Schizophrenia based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	6050	2722	3328
Unadjusted prevalence (%)	1.96	1.57	2.46
Mean age at first event (years)	32.02	33.15	31.09

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.50 [1.83, 3.43]	1.1e-8	400
15 years	0.01	1.62 [1.20, 2.17]	1.5e-3	152
5 years	0.00	2.34 [1.69, 3.25]	3.7e-7	52
1 year	0.00	4.36 [2.63, 7.24]	1.2e-8	18

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: F5_SCHZPHR – Schizophrenia
GWS hits: 0

Survival analyses between endpoints

↥

Plot

before Schizophrenia
after Schizophrenia

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Schizophrenia

↥