Schizophrenia or delusion

KRA_PSY_SCHIZODEL

schizophrenia: A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 F20-F29

Hospital discharge: ICD-9 295|29[7-8]

Hospital discharge: ICD-8 295|297|298[1-9]|299

Cause of death: ICD-10 F20-F29

Cause of death: ICD-9 295|29[7-8]

Cause of death: ICD-8 295|297|298[1-9]|299

12252

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

12142

Check minimum number of events None

12142

Include endpoints None

12142

KRA_PSY_SCHIZODEL

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Schizophrenia or delusion based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	11612	5997	5615
Unadjusted prevalence (%)	3.76	3.46	4.16
Mean age at first event (years)	34.38	35.53	33.14

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.56 [2.05, 3.20]	2.0e-16	880
15 years	0.01	1.68 [1.37, 2.06]	6.4e-7	363
5 years	0.00	3.09 [2.55, 3.76]	3.5e-30	181
1 year	0.00	5.75 [4.34, 7.60]	1.7e-34	66

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: KRA_PSY_SCHIZODEL – Schizophrenia or delusion
GWS hits: 1

Survival analyses between endpoints

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Plot

before Schizophrenia or delusion
after Schizophrenia or delusion

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Schizophrenia or delusion

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