Schizoaffective disorder

F5_SCHIZOAFF

schizoaffective disorder: A disorder in which the individual suffers from both symptoms that qualify as schizophrenia and symptoms that qualify as a mood disorder (e.g., depression or bipolar disorder) for a substantial portion (but not all) of the active period of the illness; for the remainder of the active period of the illness, the individual suffers from delusions or hallucinations in the absence of prominent mood symptoms.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 F25
Hospital discharge: ICD-9 2957
Hospital discharge: ICD-8 2957
Cause of death: ICD-10 F25
Cause of death: ICD-9 2957
Cause of death: ICD-8 2957

2621

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2621

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Check minimum number of events None

2621

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Include endpoints None

2621

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F5_SCHIZOAFF

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F20-F29
Name in latin Perturbationes schizoaffectivae

Summary Statistics

Key figures

All Female Male
Number of individuals 2518 1484 1034
Unadjusted prevalence (%) 0.82 0.86 0.77
Mean age at first event (years) 37.13 37.23 36.99

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.51 [1.57, 4.04] 1.4e-4 132
15 years 0.01 1.83 [1.12, 3.02] 1.7e-2 59
5 years 0.00 2.98 [1.75, 5.07] 6.2e-5 22
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: F5_SCHIZOAFF – Schizoaffective disorder
GWS hits: 1

Survival analyses between endpoints

Plot

before Schizoaffective disorder
after Schizoaffective disorder

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Drugs most likely to be purchased after Schizoaffective disorder