Affective disorder, aux endpoint for F5_SAD

PheWeb

F5_ADO

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 F25, F30, F31, F32, F33, F34

Hospital discharge: ICD-9 2957A|296|3004A

Hospital discharge: ICD-8 29570|296|30040|30041

Cause of death: ICD-10 F25, F30, F31, F32, F33, F34

Cause of death: ICD-9 2957A|296|3004A

Cause of death: ICD-8 29570|296|30040|30041

39574

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

39574

Check minimum number of events None

39574

Include endpoints None

39574

F5_ADO

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF6v3

Similar endpoints

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List of similar endpoints to Affective disorder, aux endpoint for F5_SAD based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	38091	24837	13254
Unadjusted prevalence (%)	12.35	14.31	9.82
Mean age at first event (years)	40.78	39.74	42.72

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.53 [2.16, 2.97]	3.0e-30	2506
15 years	0.01	1.68 [1.45, 1.96]	2.2e-11	1130
5 years	0.00	2.99 [2.62, 3.42]	4.9e-59	581
1 year	0.00	7.46 [6.29, 8.84]	<1e-100	287

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_ADO – Affective disorder, aux endpoint for F5_SAD
GWS hits:

Survival analyses between endpoints

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Plot

before Affective disorder, aux endpoint for F5_SAD
after Affective disorder, aux endpoint for F5_SAD

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Table

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Drugs most likely to be purchased after Affective disorder, aux endpoint for F5_SAD

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