Constitutional tall stature

E4_TALL

endocrine system disease: A disease involving the endocrine system.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 E34.40, E34.45
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 E34.40, E34.45
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

100

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

100

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Check minimum number of events None

100

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Include endpoints None

100

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E4_TALL

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 93 64 29
Unadjusted prevalence (%) 0.03 0.04 0.02
Mean age at first event (years) 9.24 9.03 9.71

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_TALL – Constitutional tall stature
GWS hits:

Survival analyses between endpoints

Plot

before Constitutional tall stature
after Constitutional tall stature

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Constitutional tall stature