Endocrine disorders, other/unspecified

DOID EFO MESH SNOMED PheWeb

E4_ENDODISNAS

endocrine system disease: A disease involving the endocrine system.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E34.8, E34.9

Hospital discharge: ICD-9 2592

Hospital discharge: ICD-8 2589

Cause of death: ICD-10 E34.8, E34.9

Cause of death: ICD-9 2592

Cause of death: ICD-8 2589

493

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

486

Check minimum number of events None

486

Include endpoints None

486

E4_ENDODISNAS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Endocrine disorders, other/unspecified based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	470	319	151
Unadjusted prevalence (%)	0.15	0.18	0.11
Mean age at first event (years)	42.76	40.87	46.74

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	2.81 [1.08, 7.29]	3.4e-2	33
15 years	0.02	2.28 [1.00, 5.19]	4.9e-2	17
5 years	0.01	4.73 [2.14, 10.46]	1.2e-4	10
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_ENDODISNAS – Endocrine disorders, other/unspecified
GWS hits: 0

Survival analyses between endpoints

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Plot

before Endocrine disorders, other/unspecified
after Endocrine disorders, other/unspecified

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Table

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Drugs most likely to be purchased after Endocrine disorders, other/unspecified

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