Other adrenocortical overactivity

DOID EFO MESH SNOMED PheWeb

E4_ADREACT

adrenal gland disease: A disease involving the adrenal gland.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E27.0

Hospital discharge: ICD-9 2553A

Hospital discharge: ICD-8 25508

Cause of death: ICD-10 E27.0

Cause of death: ICD-9 2553A

Cause of death: ICD-8 25508

120

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

120

Check minimum number of events None

120

Include endpoints None

120

E4_ADREACT

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 E27

Name in latin Alia hyperfunctio adrenocorticalis

Similar endpoints

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List of similar endpoints to Other adrenocortical overactivity based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	116	91	25
Unadjusted prevalence (%)	0.04	0.05	0.02
Mean age at first event (years)	25.50	21.31	40.74

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_ADREACT – Other adrenocortical overactivity
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other adrenocortical overactivity
after Other adrenocortical overactivity

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Table

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Drugs most likely to be purchased after Other adrenocortical overactivity

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