Asthma-related infections


asthma: A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors resulting in recurring periods of wheezing (a whistling sound while breathing), chest tightness, shortness of breath, mucus production and coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety.

Endpoint definition

FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None


diagram downward connector
diagram bullet

Check conditions



diagram downward connector

Filter registries None


diagram downward connector

Check pre-conditions, main-only, mode, ICD version None


diagram downward connector

Check minimum number of events None


diagram downward connector

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 16439 9373 7066
Unadjusted prevalence (%) 5.33 5.40 5.23
Mean age at first event (years) 44.22 43.85 44.71


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 3.00 [2.40, 3.75] 6.3e-22 2221
15 years 0.01 1.55 [1.29, 1.85] 2.0e-6 848
5 years 0.00 3.08 [2.67, 3.55] 7.0e-54 601
1 year 0.00 12.19 [10.44, 14.24] <1e-100 504

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: ASTHMA_INFECTIONS – Asthma-related infections
GWS hits: 12

Survival analyses between endpoints


before Asthma-related infections
after Asthma-related infections

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Asthma-related infections