Asthma-related pneumonia

ASTHMA_PNEUMONIA

pneumonia: An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, caused by an infection in one or both of the lungs (by bacteria, viruses, fungi, or mycoplasma.). Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions

J10_ASTHMA

33502

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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ASTHMA_PNEUMONIA

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 9023 4742 4281
Unadjusted prevalence (%) 2.92 2.73 3.17
Mean age at first event (years) 53.65 51.09 56.49

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.94 [4.14, 5.89] 1.5e-70 1934
15 years 0.01 1.97 [1.67, 2.31] 2.7e-16 635
5 years 0.00 4.16 [3.61, 4.80] 7.2e-85 568
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: ASTHMA_PNEUMONIA – Asthma-related pneumonia
GWS hits: 3

Survival analyses between endpoints

Plot

before Asthma-related pneumonia
after Asthma-related pneumonia

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Drugs most likely to be purchased after Asthma-related pneumonia