Pre-eclampsia superimposed on chronic hypertension

O15_PREECLAMPS_CHRONIC_HYPERT

hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule

Sex only females

180574

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Check conditions None

180574

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Filter registries

Hospital Discharge: ICD-10 O11
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 O11
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

123

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

123

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Check minimum number of events None

123

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Include endpoints None

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O15_PREECLAMPS_CHRONIC_HYPERT

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF3
Parent code in ICD-10 O10-O16
Name in latin Hypertensio prae-existens cum proteinuria superposita

Summary Statistics

Key figures

All Female Male
Number of individuals 121 121 -
Unadjusted prevalence (%) 0.04 0.07 -
Mean age at first event (years) 33.88 33.88 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: O15_PREECLAMPS_CHRONIC_HYPERT – Pre-eclampsia superimposed on chronic hypertension
GWS hits: 0

Survival analyses between endpoints

Plot

before Pre-eclampsia superimposed on chronic hypertension
after Pre-eclampsia superimposed on chronic hypertension

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Drugs most likely to be purchased after Pre-eclampsia superimposed on chronic hypertension