Gout

M13_GOUT

gout: A condition characterized by painful swelling of the joints, which is caused by deposition of urate crystals.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 M10
Hospital discharge: ICD-9 2740
Hospital discharge: ICD-8 2740
Cause of death: ICD-10 M10
Cause of death: ICD-9 2740
Cause of death: ICD-8 2740
KELA reimbursements: KELA codes 212

6232

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

6232

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Check minimum number of events None

6232

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Include endpoints None

6232

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M13_GOUT

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M05-M14

Summary Statistics

Key figures

All Female Male
Number of individuals 6031 1404 4627
Unadjusted prevalence (%) 1.95 0.81 3.43
Mean age at first event (years) 64.30 66.45 63.65

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.39 [1.83, 3.13] 2.1e-10 1264
15 years 0.01 1.10 [0.86, 1.41] 4.5e-1 436
5 years 0.00 3.30 [2.71, 4.03] 8.8e-32 436
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_GOUT – Gout
GWS hits: 7

Survival analyses between endpoints

Plot

before Gout
after Gout

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