Idiopathic gout

GOUT_IDIO

gout: A condition characterized by painful swelling of the joints, which is caused by deposition of urate crystals.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 M10.0
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M10.0
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

1587

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1587

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Check minimum number of events None

1587

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Include endpoints None

1587

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GOUT_IDIO

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 M10
Name in latin Arthritis urica idiopathica

Summary Statistics

Key figures

All Female Male
Number of individuals 1541 302 1239
Unadjusted prevalence (%) 0.50 0.17 0.92
Mean age at first event (years) 65.63 67.57 65.15

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.74 [2.53, 5.51] 3.0e-11 312
15 years 0.01 1.57 [1.03, 2.39] 3.6e-2 116
5 years 0.00 4.27 [3.15, 5.78] 7.4e-21 121
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: GOUT_IDIO – Idiopathic gout
GWS hits: 3

Survival analyses between endpoints

Plot

before Idiopathic gout
after Idiopathic gout

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