Gout, FINNGEN

GOUT

gout: A condition characterized by painful swelling of the joints, which is caused by deposition of urate crystals.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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GOUT

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 6031 1404 4627
Unadjusted prevalence (%) 1.95 0.81 3.43
Mean age at first event (years) 64.30 66.45 63.65

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.98 [2.36, 3.77] 8.1e-20 1264
15 years 0.01 1.35 [1.11, 1.65] 2.8e-3 436
5 years 0.00 3.59 [3.03, 4.26] 3.1e-49 436
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: GOUT – Gout, FINNGEN
GWS hits: 8

Survival analyses between endpoints

Plot

before Gout, FINNGEN
after Gout, FINNGEN

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