Gonarthrosis,primary

MESH PheWeb

M13_ARTHROSIS_KNEE_PRIM_ICD10

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M17.0, M17.1

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 M17.0, M17.1

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

31722

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

31722

Check minimum number of events None

31722

Include endpoints None

31722

M13_ARTHROSIS_KNEE_PRIM_ICD10

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF3

Similar endpoints

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List of similar endpoints to Gonarthrosis,primary based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	30904	18546	12358
Unadjusted prevalence (%)	10.02	10.69	9.15
Mean age at first event (years)	60.50	60.34	60.75

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.15 [1.01, 1.31]	3.7e-2	2323
15 years	0.01	0.88 [0.78, 1.00]	4.5e-2	1330
5 years	0.00	1.24 [1.09, 1.40]	8.1e-4	512
1 year	0.00	1.31 [1.04, 1.64]	1.9e-2	100

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_ARTHROSIS_KNEE_PRIM_ICD10 – Gonarthrosis,primary
GWS hits: 14

Survival analyses between endpoints

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Plot

before Gonarthrosis,primary
after Gonarthrosis,primary

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Table

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Drugs most likely to be purchased after Gonarthrosis,primary

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