Malignant neoplasm, wide definition for exclusion

C3_CANCER_WIDE

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 C
Hospital discharge: ICD-9 1[4-9]|20
Hospital discharge: ICD-8 1[4-9]|20
Cause of death: ICD-10 C
Cause of death: ICD-9 1[4-9]|20
Cause of death: ICD-8 1[4-9]|20
KELA reimbursements: KELA codes 115|116

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy 1
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 70476 36239 34237
Unadjusted prevalence (%) 22.84 20.88 25.36
Mean age at first event (years) 61.28 57.52 65.26

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 4.05 [3.73, 4.41] <1e-100 13401
15 years 0.01 1.80 [1.64, 1.98] 5.9e-34 4070
5 years 0.00 5.38 [4.97, 5.82] <1e-100 3981
1 year 0.00 26.87 [23.77, 30.39] <1e-100 4309

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: C3_CANCER_WIDE – Malignant neoplasm, wide definition for exclusion
GWS hits:

Survival analyses between endpoints

Plot

before Malignant neoplasm, wide definition for exclusion
after Malignant neoplasm, wide definition for exclusion

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Drugs most likely to be purchased after Malignant neoplasm, wide definition for exclusion