Malignant neoplasm of skin

C3_SKIN

skin neoplasm: A benign or malignant tumor involving the skin. Representative examples of benign skin neoplasms include the benign melanocytic skin nevus, acanthoma, sebaceous adenoma, sweat gland adenoma, lipoma, hemangioma, fibroma, and benign fibrous histiocytoma. Representative examples of malignant skin neoplasms include basal cell carcinoma, squamous cell carcinoma, melanoma, and Kaposi sarcoma.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

16499

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C3_SKIN

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 16021 7585 8436
Unadjusted prevalence (%) 5.19 4.37 6.25
Mean age at first event (years) 64.69 62.78 66.41

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.53 [1.29, 1.83] 2.1e-6 2486
15 years 0.01 0.92 [0.80, 1.07] 2.9e-1 1113
5 years 0.00 1.89 [1.67, 2.12] 2.1e-25 788
1 year 0.00 3.21 [2.71, 3.79] 5.4e-42 268

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: C3_SKIN – Malignant neoplasm of skin
GWS hits: 53

Survival analyses between endpoints

Plot

before Malignant neoplasm of skin
after Malignant neoplasm of skin

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Drugs most likely to be purchased after Malignant neoplasm of skin