Other malignant neoplasms of skin (=non-melanoma skin cancer)

C3_OTHER_SKIN

skin neoplasm: A benign or malignant tumor involving the skin. Representative examples of benign skin neoplasms include the benign melanocytic skin nevus, acanthoma, sebaceous adenoma, sweat gland adenoma, lipoma, hemangioma, fibroma, and benign fibrous histiocytoma. Representative examples of malignant skin neoplasms include basal cell carcinoma, squamous cell carcinoma, melanoma, and Kaposi sarcoma.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions

not C3_MELANOMA_SKIN

318790

Filter registries

Cause of death: ICD-10 C44

Cause of death: ICD-9 173

Cause of death: ICD-8 173

Cancer registry: Topography ICD-O-3 C44

13987

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

13987

Check minimum number of events None

13987

Include endpoints None

13987

C3_OTHER_SKIN

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF6v3

Similar endpoints

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List of similar endpoints to Other malignant neoplasms of skin (=non-melanoma skin cancer) based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	13555	6379	7176
Unadjusted prevalence (%)	4.39	3.68	5.31
Mean age at first event (years)	65.54	63.97	66.93

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.41 [1.20, 1.67]	4.9e-5	2172
15 years	0.01	0.89 [0.77, 1.02]	9.5e-2	1022
5 years	0.00	1.65 [1.45, 1.88]	2.2e-14	665
1 year	0.00	2.52 [2.10, 3.03]	6.7e-23	199

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: C3_OTHER_SKIN – Other malignant neoplasms of skin (=non-melanoma skin cancer)
GWS hits: 53

Survival analyses between endpoints

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Plot

before Other malignant neoplasms of skin (=non-melanoma skin cancer)
after Other malignant neoplasms of skin (=non-melanoma skin cancer)

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Table

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Drugs most likely to be purchased after Other malignant neoplasms of skin (=non-melanoma skin cancer)

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