Malignant neoplasm of eye, brain and central nervous system

C3_EYE_BRAIN_NEURO

brain neoplasm: A neoplasm (disease) that involves the brain.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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C3_EYE_BRAIN_NEURO

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF4

Similar endpoints

List of similar endpoints to Malignant neoplasm of eye, brain and central nervous system based on the number of shared cases.

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Summary Statistics

Key figures

All Female Male
Number of individuals 2111 1256 855
Unadjusted prevalence (%) 0.68 0.72 0.63
Mean age at first event (years) 53.76 53.05 54.81

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 5.45 [3.64, 8.17] 2.1e-16 449
15 years 0.01 1.60 [1.05, 2.43] 2.7e-2 100
5 years 0.01 5.63 [3.71, 8.54] 4.4e-16 117
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: C3_EYE_BRAIN_NEURO – Malignant neoplasm of eye, brain and central nervous system
GWS hits: 0

Survival analyses between endpoints

Plot

before Malignant neoplasm of eye, brain and central nervous system
after Malignant neoplasm of eye, brain and central nervous system

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Drugs most likely to be purchased after Malignant neoplasm of eye, brain and central nervous system