Brain glioblastoma


brain glioblastoma: A WHO grade IV malignant astrocytic tumor that arises from the brain, usually the cerebral hemispheres. It is characterized by the presence of poorly differentiated astrocytes, cellular polymorphism, nuclear atypia, and increased mitotic activity. The prognosis is poor.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions



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Filter registries

Cause of death: ICD-10 C71
Cause of death: ICD-9 191
Cause of death: ICD-8 191
Cancer registry: Topography ICD-O-3 C71
Cancer registry: Morphology ICD-O-3 9440
Cancer registry: Behaviour codes 3


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 155 68 87
Unadjusted prevalence (%) 0.05 0.04 0.06
Mean age at first event (years) 63.67 64.38 63.11


Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: C3_GBM – Brain glioblastoma
GWS hits: 0

Survival analyses between endpoints


before Brain glioblastoma
after Brain glioblastoma

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Drugs most likely to be purchased after Brain glioblastoma