Malignant neoplasm of brain

DOID EFO MESH PheWeb

C3_BRAIN

brain neoplasm: A neoplasm (disease) that involves the brain.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Cause of death: ICD-10 C71

Cause of death: ICD-9 191

Cause of death: ICD-8 191

Cancer registry: Topography ICD-O-3 C71

730

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

730

Check minimum number of events None

730

Include endpoints None

730

C3_BRAIN

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF4

Similar endpoints

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List of similar endpoints to Malignant neoplasm of brain based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	692	325	367
Unadjusted prevalence (%)	0.22	0.19	0.27
Mean age at first event (years)	48.94	46.25	51.33

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.45	46.44 [27.73, 77.79]	3.5e-48	241
15 years	0.04	6.49 [3.85, 10.93]	2.1e-12	26
5 years	0.04	33.45 [21.66, 51.65]	2.0e-56	69
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: C3_BRAIN – Malignant neoplasm of brain
GWS hits: 1

Survival analyses between endpoints

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Plot

before Malignant neoplasm of brain
after Malignant neoplasm of brain

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Table

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Drugs most likely to be purchased after Malignant neoplasm of brain

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