Brain astrocytoma

C3_ASTROCYTOMA

astrocytoma: A glial tumor of the brain or spinal cord showing astrocytic differentiation. It includes the following clinicopathological entities: pilocytic astrocytoma, diffuse astrocytoma, anaplastic astrocytoma, pleomorphic xanthoastrocytoma, subependymal giant cell astrocytoma, and glioblastoma.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions

HLP_C3_ASTROCYTOMA

Filter registries

Cause of death: ICD-10 C71

Cause of death: ICD-9 191

Cause of death: ICD-8 191

Cancer registry: Topography ICD-O-3 C71

Cancer registry: Morphology ICD-O-3 9400

Cancer registry: Behaviour codes 3

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

C3_ASTROCYTOMA

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF4

Similar endpoints

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List of similar endpoints to Brain astrocytoma based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	52	20	32
Unadjusted prevalence (%)	0.02	0.01	0.02
Mean age at first event (years)	42.08	41.86	42.22

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: C3_ASTROCYTOMA – Brain astrocytoma
GWS hits:

Survival analyses between endpoints

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Plot

before Brain astrocytoma
after Brain astrocytoma

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Table

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Drugs most likely to be purchased after Brain astrocytoma

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