Malignant neoplasm of meninges

C3_MENINGES

obsolete_meningioma: ['A tumor of meningothelial cells that are manifested in the central nervous system and arise from the arachnoid "cap" cells of the arachnoid villi in the meninges.']

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Cause of death: ICD-10 C70
Cause of death: ICD-9 1921|1923
Cause of death: ICD-8 192[1-2]
Cancer registry: Topography ICD-O-3 C70

1002

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

1002

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Check minimum number of events None

1002

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Include endpoints None

1002

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C3_MENINGES

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 969 708 261
Unadjusted prevalence (%) 0.31 0.41 0.19
Mean age at first event (years) 58.21 57.32 60.62

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.32 [1.22, 4.43] 1.1e-2 141
15 years 0.01 1.27 [0.73, 2.20] 4.0e-1 50
5 years 0.00 2.03 [1.21, 3.43] 7.7e-3 22
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: C3_MENINGES – Malignant neoplasm of meninges
GWS hits: 1

Survival analyses between endpoints

Plot

before Malignant neoplasm of meninges
after Malignant neoplasm of meninges

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Drugs most likely to be purchased after Malignant neoplasm of meninges