Ulcerative colitis, NAS


ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 K51.9
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 K51.9
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K51
Name in latin Colitis ulcerosa non specificata

Summary Statistics

Key figures

All Female Male
Number of individuals 3438 1882 1556
Unadjusted prevalence (%) 1.11 1.08 1.15
Mean age at first event (years) 46.30 44.49 48.48


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.33 [1.49, 3.64] 2.1e-4 221
15 years 0.01 1.29 [0.82, 2.00] 2.7e-1 96
5 years 0.00 2.75 [1.86, 4.05] 3.6e-7 59
1 year 0.00 10.23 [6.79, 15.42] 1.2e-28 42

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: ULCERNAS – Ulcerative colitis, NAS
GWS hits: 5

Survival analyses between endpoints


before Ulcerative colitis, NAS
after Ulcerative colitis, NAS

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Drugs most likely to be purchased after Ulcerative colitis, NAS