Ulcerative ileocolitis

ULCERILEO

Crohn's disease: A gastrointestinal disorder characterized by chronic inflammation involving all layers of the intestinal wall, noncaseating granulomas affecting the intestinal wall and regional lymph nodes, and transmural fibrosis. Crohn disease most commonly involves the terminal ileum; the colon is the second most common site of involvement.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 K51.1

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 K51.1

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

996

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

996

Check minimum number of events None

996

Include endpoints None

996

ULCERILEO

Extra metadata

First used in FinnGen datafreeze DF2

Parent code in ICD-10 K51

Name in latin Ileocolitis ulcerosa [chronica]

Similar endpoints

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List of similar endpoints to Ulcerative ileocolitis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	973	517	456
Unadjusted prevalence (%)	0.32	0.30	0.34
Mean age at first event (years)	43.36	41.19	45.82

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.42 [0.66, 3.05]	3.7e-1	40
15 years	0.00	0.82 [0.34, 1.96]	6.5e-1	19
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ULCERILEO – Ulcerative ileocolitis
GWS hits: 1

Survival analyses between endpoints

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Plot

before Ulcerative ileocolitis
after Ulcerative ileocolitis

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Table

Loading survival analyses table

Drugs most likely to be purchased after Ulcerative ileocolitis

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