Medication related adverse effects (Asthma/COPD)

PheWeb

PULM_MEDICATIO_COMORB

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

H7_CATARACTSENILE

H7_CATARACTOTHER

M13_OSTEOPOROSIS

R18_RETEN_URINE

ST19_FRACT_FEMUR

59871

PULM_MEDICATIO_COMORB

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Medication related adverse effects (Asthma/COPD) based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	57975	29951	28024
Unadjusted prevalence (%)	18.79	17.26	20.76
Mean age at first event (years)	68.00	67.55	68.49

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	2.71 [2.48, 2.96]	<1e-100	11551
15 years	0.01	1.52 [1.38, 1.66]	3.7e-19	5323
5 years	0.00	2.82 [2.61, 3.05]	<1e-100	3966
1 year	0.00	4.83 [4.31, 5.41]	<1e-100	1472

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: PULM_MEDICATIO_COMORB – Medication related adverse effects (Asthma/COPD)
GWS hits:

Survival analyses between endpoints

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Plot

before Medication related adverse effects (Asthma/COPD)
after Medication related adverse effects (Asthma/COPD)

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Table

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Drugs most likely to be purchased after Medication related adverse effects (Asthma/COPD)

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