Other cataract

H7_CATARACTOTHER

cataract: Partial or complete opacity of the crystalline lens of one or both eyes that decreases visual acuity and eventually results in blindness. Some cataracts appear in infancy or in childhood, but most develop in older individuals. (Sternberg Diagnostic Surgical Pathology, 3rd ed.)

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H26

Hospital discharge: ICD-9 366

Hospital discharge: ICD-8 374

Hospital discharge: excluded ICD-9 3661

Hospital discharge: excluded ICD-8 37403

Cause of death: ICD-10 H26

Cause of death: ICD-9 366

Cause of death: ICD-8 374

Cause of death: excluded ICD-9 3661

Cause of death: excluded ICD-8 37403

13329

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

13017

Check minimum number of events None

13017

Include endpoints None

13017

H7_CATARACTOTHER

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H25-H28

Name in latin Alia cataracta

Similar endpoints

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List of similar endpoints to Other cataract based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Drug-induced cataract

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	12634	7311	5323
Unadjusted prevalence (%)	4.09	4.21	3.94
Mean age at first event (years)	65.68	66.36	64.76

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	1.99 [1.62, 2.43]	2.6e-11	1902
15 years	0.01	1.18 [0.99, 1.40]	6.6e-2	927
5 years	0.00	2.10 [1.82, 2.43]	4.6e-24	638
1 year	0.00	2.64 [2.16, 3.24]	6.0e-21	159

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_CATARACTOTHER – Other cataract
GWS hits: 7

Survival analyses between endpoints

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Plot

before Other cataract
after Other cataract

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Table

Loading survival analyses table

Drugs most likely to be purchased after Other cataract

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