Medication related adverse effects

PheWeb

ASTHMA_MEDICATIO_COMORB

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

H7_CATARACTSENILE

H7_CATARACTOTHER

M13_OSTEOPOROSIS

R18_RETEN_URINE

56497

ASTHMA_MEDICATIO_COMORB

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Medication related adverse effects based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	54742	28546	26196
Unadjusted prevalence (%)	17.74	16.45	19.40
Mean age at first event (years)	68.63	68.02	69.30

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	2.58 [2.34, 2.84]	6.6e-83	10522
15 years	0.01	1.52 [1.39, 1.67]	3.5e-19	5010
5 years	0.00	2.68 [2.49, 2.89]	<1e-100	3645
1 year	0.00	3.97 [3.53, 4.45]	<1e-100	1157

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ASTHMA_MEDICATIO_COMORB – Medication related adverse effects
GWS hits:

Survival analyses between endpoints

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Plot

before Medication related adverse effects
after Medication related adverse effects

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Table

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Drugs most likely to be purchased after Medication related adverse effects

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