Gestational [pregnancy-induced] hypertension

O15_GESTAT_HYPERT

preeclampsia: Preeclampsia is a hypertensive disorder of pregnancy that is characterized by new-onset hypertension with proteinuria presenting after 20 weeks of gestation, and depending on mild or severe forms may initially present with severe headache, visual disturbances, and hyperreflexia.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule

Sex only females

180574

Check conditions None

180574

Filter registries

Hospital Discharge: ICD-10 O13

Hospital discharge: ICD-9 6423

Hospital discharge: ICD-8 63701

Cause of death: ICD-10 O13

Cause of death: ICD-9 6423

Cause of death: ICD-8 63701

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

6731

O15_GESTAT_HYPERT

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF5

Parent code in ICD-10 O10-O16

Name in latin Hypertensio gestationalis sine proteinuria significanti

Similar endpoints

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List of similar endpoints to Gestational [pregnancy-induced] hypertension based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	6562	6562	-
Unadjusted prevalence (%)	2.13	3.78	-
Mean age at first event (years)	30.05	30.05	-

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	1.08 [0.77, 1.53]	6.6e-1	117
15 years	0.01	0.90 [0.61, 1.34]	6.2e-1	50
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: O15_GESTAT_HYPERT – Gestational [pregnancy-induced] hypertension
GWS hits: 3

Survival analyses between endpoints

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Plot

before Gestational [pregnancy-induced] hypertension
after Gestational [pregnancy-induced] hypertension

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Table

Loading survival analyses table

Drugs most likely to be purchased after Gestational [pregnancy-induced] hypertension

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