Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

O15_EXIST_HYPERT_COMPLIC

hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

Endpoint definition

FinnGen phenotype data

321302 individuals

diagram downward connector
diagram bullet

Apply sex-specific rule

Sex only females

180574

diagram downward connector

Check conditions None

180574

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 O10
Hospital discharge: ICD-9 6420
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 O10
Cause of death: ICD-9 6420
Cause of death: ICD-8 $!$

1703

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1698

diagram downward connector

Check minimum number of events None

1698

diagram downward connector

Include endpoints None

1698

diagram downward connector
O15_EXIST_HYPERT_COMPLIC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF3
Parent code in ICD-10 O10-O16
Name in latin Hypertensio prae-existens graviditatem, partum et/sive puerperium complicans

Summary Statistics

Key figures

All Female Male
Number of individuals 1661 1661 -
Unadjusted prevalence (%) 0.54 0.96 -
Mean age at first event (years) 32.95 32.95 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.48 [0.67, 3.28] 3.3e-1 15
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: O15_EXIST_HYPERT_COMPLIC – Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
GWS hits: 1

Survival analyses between endpoints

Plot

before Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
after Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Pre-existing hypertension complicating pregnancy, childbirth and the puerperium