Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

O15_EXIST_HYPERT_COMPLIC

hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule

Sex only females

180574

Check conditions None

180574

Filter registries

Hospital Discharge: ICD-10 O10

Hospital discharge: ICD-9 6420

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 O10

Cause of death: ICD-9 6420

Cause of death: ICD-8 $!$

1703

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1698

Check minimum number of events None

1698

Include endpoints None

1698

O15_EXIST_HYPERT_COMPLIC

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF3

Parent code in ICD-10 O10-O16

Name in latin Hypertensio prae-existens graviditatem, partum et/sive puerperium complicans

Similar endpoints

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List of similar endpoints to Pre-existing hypertension complicating pregnancy, childbirth and the puerperium based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1661	1661	-
Unadjusted prevalence (%)	0.54	0.96	-
Mean age at first event (years)	32.95	32.95	-

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.48 [0.67, 3.28]	3.3e-1	15
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: O15_EXIST_HYPERT_COMPLIC – Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
GWS hits: 1

Survival analyses between endpoints

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Plot

before Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
after Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

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Table

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Drugs most likely to be purchased after Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

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