Mucosal proctocolitis

MUCOPROCT

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 K51.5

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 K51.5

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

3129

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

3129

Check minimum number of events None

3129

Include endpoints None

3129

MUCOPROCT

Extra metadata

First used in FinnGen datafreeze DF2

Parent code in ICD-10 K51

Name in latin Proctocolitis mucosalis

Similar endpoints

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List of similar endpoints to Mucosal proctocolitis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Colitis, primary sclerosing, strict definition

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	3037	1532	1505
Unadjusted prevalence (%)	0.98	0.88	1.11
Mean age at first event (years)	44.88	42.59	47.20

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.67 [1.13, 2.46]	9.7e-3	120
15 years	0.01	1.16 [0.78, 1.74]	4.6e-1	64
5 years	0.00	1.92 [1.23, 3.01]	4.2e-3	29
1 year	0.00	4.74 [2.62, 8.56]	2.6e-7	14

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: MUCOPROCT – Mucosal proctocolitis
GWS hits: 9

Survival analyses between endpoints

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Plot

before Mucosal proctocolitis
after Mucosal proctocolitis

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Table

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Drugs most likely to be purchased after Mucosal proctocolitis

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