Motor neuron disease (with DMD)

DOID EFO MESH PheWeb

MND

muscular disease: Acquired, familial, and congenital disorders of skeletal muscle and smooth muscle.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 G71.06

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 G71.06

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints

G6_ALS

383

MND

Extra metadata

First used in FinnGen datafreeze DF3

Parent code in ICD-10 G710

Name in latin Dystrophia musculorum gravis (Duchenne)

Similar endpoints

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List of similar endpoints to Motor neuron disease (with DMD) based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Motor neuron disease

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	375	138	237
Unadjusted prevalence (%)	0.12	0.08	0.18
Mean age at first event (years)	62.29	63.40	61.64

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: MND – Motor neuron disease (with DMD)
GWS hits: 3

Survival analyses between endpoints

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Plot

before Motor neuron disease (with DMD)
after Motor neuron disease (with DMD)

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Table

Loading survival analyses table

Drugs most likely to be purchased after Motor neuron disease (with DMD)

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