≡ Risteys
R7

Documentation Changelog GitHub Contact & Feedback

Polyarteritis nodosa and related conditions

DOIDEFOMESH PheWeb

M13_POLYARTERETAL

Polyarteritis Nodosa: ['A necrotizing vasculitis that affects medium-sized arteries, it is usually idiopathic, and may be triggered by viral infections (Hepatitis B, also others). A multisystem disease, it most commonly affects skin (nodules, livedo reticularis) and peripheral nerves; higher morbidity is associated with gastrointestinal, central nervous system, cardiac, and/or other organ involvement. Anti-neutrophil cytoplasmic antibodies (ANCA) are typically negative. [ NCI ]']

Endpoint definition

↥
FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None

321302

diagram downward connector

Check conditions None

321302

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 M30
Cause of death: ICD-10 M30

287

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

287

diagram downward connector

Check minimum number of events None

287

diagram downward connector
diagram bullet diagram downward connector

Include endpoints

306

diagram downward connector
M13_POLYARTERETAL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M30-M36
Name in latin Polyarteritis nodosa et condiciones cognatae

Similar endpoints

↥

List of similar endpoints to Polyarteritis nodosa and related conditions based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 295 176 119
Unadjusted prevalence (%) 0.10 0.10 0.09
Mean age at first event (years) 48.44 47.62 49.64

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 7.22 [4.37, 11.95] 1.4e-14 42
15 years 0.01 2.33 [1.26, 4.31] 6.8e-3 13
5 years 0.01 4.79 [2.43, 9.42] 5.8e-6 14
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: M13_POLYARTERETAL – Polyarteritis nodosa and related conditions
GWS hits:

Survival analyses between endpoints

↥

Plot

before Polyarteritis nodosa and related conditions
after Polyarteritis nodosa and related conditions

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Polyarteritis nodosa and related conditions

↥