Polyarteritis nodosa

M13_POLNODOSA

Polyarteritis Nodosa: ['A necrotizing vasculitis that affects medium-sized arteries, it is usually idiopathic, and may be triggered by viral infections (Hepatitis B, also others). A multisystem disease, it most commonly affects skin (nodules, livedo reticularis) and peripheral nerves; higher morbidity is associated with gastrointestinal, central nervous system, cardiac, and/or other organ involvement. Anti-neutrophil cytoplasmic antibodies (ANCA) are typically negative. [ NCI ]']

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M30.0

Hospital discharge: ICD-9 4460A

Hospital discharge: ICD-8 4460

Cause of death: ICD-10 M30.0

Cause of death: ICD-9 4460A

Cause of death: ICD-8 4460

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

145

M13_POLNODOSA

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M30

Name in latin Polyarteritis nodosa

Similar endpoints

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List of similar endpoints to Polyarteritis nodosa based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	143	81	62
Unadjusted prevalence (%)	0.05	0.05	0.05
Mean age at first event (years)	55.10	53.80	56.79

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_POLNODOSA – Polyarteritis nodosa
GWS hits: 0

Survival analyses between endpoints

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Plot

before Polyarteritis nodosa
after Polyarteritis nodosa

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Table

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Drugs most likely to be purchased after Polyarteritis nodosa

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