Urticaria and erythema

L12_URTICARIAERYTHEMA

urticaria: A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 L50-L54
Cause of death: ICD-10 L50-L54

8033

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

8033

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Check minimum number of events None

8033

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L12_URTICARIAERYTHEMA

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 9663 6719 2944
Unadjusted prevalence (%) 3.13 3.87 2.18
Mean age at first event (years) 41.97 41.36 43.36

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.27 [1.66, 3.10] 2.8e-7 491
15 years 0.01 1.45 [1.08, 1.93] 1.3e-2 225
5 years 0.00 2.60 [2.02, 3.35] 1.0e-13 123
1 year 0.00 4.95 [3.49, 7.02] 2.9e-19 45

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_URTICARIAERYTHEMA – Urticaria and erythema
GWS hits: 1

Survival analyses between endpoints

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Plot

before Urticaria and erythema
after Urticaria and erythema

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Urticaria and erythema

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