Urticaria and erythema

L12_URTICARIAERYTHEMA

urticaria: A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 L50-L54
Cause of death: ICD-10 L50-L54

8033

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

8033

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Check minimum number of events None

8033

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L12_URTICARIAERYTHEMA

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 9663 6719 2944
Unadjusted prevalence (%) 3.13 3.87 2.18
Mean age at first event (years) 41.97 41.36 43.36

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.27 [1.66, 3.10] 2.8e-7 491
15 years 0.01 1.45 [1.08, 1.93] 1.3e-2 225
5 years 0.00 2.60 [2.02, 3.35] 1.0e-13 123
1 year 0.00 4.95 [3.49, 7.02] 2.9e-19 45

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: L12_URTICARIAERYTHEMA – Urticaria and erythema
GWS hits: 1

Survival analyses between endpoints

Plot

before Urticaria and erythema
after Urticaria and erythema

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Urticaria and erythema