Dermatographic urticaria

L12_URTICA_DERTMATOG

dermatographia: Familial dermographism is a condition also known as skin writing. When people who have dermatographia lightly scratch their skin, the scratches redden into a raised wheal similar to hives. Signs and symptoms of dermatographia include raised red lines, swelling, inflammation, hive-like welts and itching. Symptoms usually disappear within 30 minutes. The exact cause of this condition is unknown. Treatment mayinvovle use of antihistamines if symptoms do not go away on their own.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 L50.3
Hospital discharge: ICD-9 7083
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 L50.3
Cause of death: ICD-9 7083
Cause of death: ICD-8 $!$

1451

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1451

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Check minimum number of events None

1451

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Include endpoints None

1451

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L12_URTICA_DERTMATOG

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L50
Name in latin Urticaria derm[at]ographica

Summary Statistics

Key figures

All Female Male
Number of individuals 1395 1092 303
Unadjusted prevalence (%) 0.45 0.63 0.22
Mean age at first event (years) 45.34 44.20 49.42

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.41 [1.14, 5.09] 2.1e-2 34
15 years 0.01 1.19 [0.53, 2.64] 6.7e-1 13
5 years 0.00 3.90 [1.86, 8.15] 3.0e-4 14
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: L12_URTICA_DERTMATOG – Dermatographic urticaria
GWS hits: 0

Survival analyses between endpoints

Plot

before Dermatographic urticaria
after Dermatographic urticaria

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Drugs most likely to be purchased after Dermatographic urticaria