Dermatographic urticaria

L12_URTICA_DERTMATOG

dermatographia: Familial dermographism is a condition also known as skin writing. When people who have dermatographia lightly scratch their skin, the scratches redden into a raised wheal similar to hives. Signs and symptoms of dermatographia include raised red lines, swelling, inflammation, hive-like welts and itching. Symptoms usually disappear within 30 minutes. The exact cause of this condition is unknown. Treatment mayinvovle use of antihistamines if symptoms do not go away on their own.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 L50.3

Hospital discharge: ICD-9 7083

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 L50.3

Cause of death: ICD-9 7083

Cause of death: ICD-8 $!$

1451

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1451

Check minimum number of events None

1451

Include endpoints None

1451

L12_URTICA_DERTMATOG

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 L50

Name in latin Urticaria derm[at]ographica

Similar endpoints

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List of similar endpoints to Dermatographic urticaria based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1395	1092	303
Unadjusted prevalence (%)	0.45	0.63	0.22
Mean age at first event (years)	45.34	44.20	49.42

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.41 [1.14, 5.09]	2.1e-2	34
15 years	0.01	1.19 [0.53, 2.64]	6.7e-1	13
5 years	0.00	3.90 [1.86, 8.15]	3.0e-4	14
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_URTICA_DERTMATOG – Dermatographic urticaria
GWS hits: 0

Survival analyses between endpoints

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Plot

before Dermatographic urticaria
after Dermatographic urticaria

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Table

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Drugs most likely to be purchased after Dermatographic urticaria

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