Other and unspecified urticaria

L12_URTICA_NAS

urticaria: A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 L50.8, L50.9

Hospital discharge: ICD-9 708[8-9]

Hospital discharge: ICD-8 708

Cause of death: ICD-10 L50.8, L50.9

Cause of death: ICD-9 708[8-9]

Cause of death: ICD-8 708

5394

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

5135

Check minimum number of events None

5135

Include endpoints None

5135

L12_URTICA_NAS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other and unspecified urticaria based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	4940	3505	1435
Unadjusted prevalence (%)	1.60	2.02	1.06
Mean age at first event (years)	39.98	39.94	40.09

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.16 [0.68, 1.97]	6.0e-1	200
15 years	0.01	0.86 [0.54, 1.36]	5.1e-1	92
5 years	0.00	1.73 [1.12, 2.67]	1.4e-2	49
1 year	0.00	3.23 [1.81, 5.79]	7.9e-5	17

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_URTICA_NAS – Other and unspecified urticaria
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other and unspecified urticaria
after Other and unspecified urticaria

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Table

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Drugs most likely to be purchased after Other and unspecified urticaria

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