Mood disorders

KRA_PSY_MOOD

mood disorder: A cognitive disorder a disturbance in which the person's mood is hypothesized to be the main underlying feature.

Endpoint definition

FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None

321302

diagram downward connector

Check conditions None

321302

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 F30-F39
Hospital discharge: ICD-9 296|3004A|3011D
Hospital discharge: ICD-8 296|29800|3004|30110
Cause of death: ICD-10 F30-F39
Cause of death: ICD-9 296|3004A|3011D
Cause of death: ICD-8 296|29800|3004|30110

39199

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

39199

diagram downward connector

Check minimum number of events None

39199

diagram downward connector

Include endpoints None

39199

diagram downward connector
KRA_PSY_MOOD

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 37733 24674 13059
Unadjusted prevalence (%) 12.23 14.22 9.67
Mean age at first event (years) 40.86 39.78 42.90

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.41 [2.05, 2.83] 1.5e-26 2480
15 years 0.01 1.60 [1.39, 1.84] 1.0e-10 1105
5 years 0.00 2.97 [2.61, 3.37] 1.5e-62 583
1 year 0.00 7.47 [6.33, 8.82] <1e-100 287

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: KRA_PSY_MOOD – Mood disorders
GWS hits: 4

Survival analyses between endpoints

Plot

before Mood disorders
after Mood disorders

loading spinner Loading survival analyses plot