Valvular operations

DOID MESH PheWeb

I9_VALVES

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Operations: NOMESCO codes ^FGA|^FGC|^FGD|^FGE|^FGW|^F^JE|^F^JF|^FK|^FM

Operations: Finnish Hospital League codes ^5261$|^527|^528|^529|^530

61389

Check pre-conditions, main-only, mode, ICD version None

61389

Check minimum number of events None

61389

Include endpoints None

61389

I9_VALVES

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Valvular operations based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	59338	28439	30899
Unadjusted prevalence (%)	19.23	16.39	22.88
Mean age at first event (years)	61.18	59.55	62.68

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	3.41 [3.04, 3.84]	1.1e-93	6239
15 years	0.01	1.68 [1.50, 1.89]	1.5e-18	2417
5 years	0.00	3.80 [3.48, 4.14]	<1e-100	2379
1 year	0.00	9.70 [8.65, 10.86]	<1e-100	1298

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_VALVES – Valvular operations
GWS hits: 10

Survival analyses between endpoints

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Plot

before Valvular operations
after Valvular operations

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Valvular operations

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