Nonischemic cardiomyopathy

I9_NONISCHCARDMYOP_STRICT

dilated cardiomyopathy: Cardiomyopathy which is characterized by dilation and contractile dysfunction of the left and right ventricles. It may be idiopathic, or it may result from a myocardial infarction, myocardial infection, or alcohol abuse. It is a cause of congestive heart failure.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions

not I9_IHD

and not I9_HYPERTROCARDMYOP

270592

Filter registries

Hospital Discharge: ICD-10 I42.0, I51.1

Hospital discharge: ICD-9 4281

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 I42.0, I51.1

Cause of death: ICD-9 4281

Cause of death: ICD-8 $!$

1342

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1342

Check minimum number of events None

1342

Include endpoints None

1342

I9_NONISCHCARDMYOP_STRICT

Extra metadata

First used in FinnGen datafreeze DF3

Similar endpoints

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List of similar endpoints to Nonischemic cardiomyopathy based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1310	382	928
Unadjusted prevalence (%)	0.42	0.22	0.69
Mean age at first event (years)	57.39	55.98	57.98

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.09	6.74 [4.31, 10.54]	6.0e-17	172
15 years	0.02	3.19 [1.99, 5.13]	1.6e-6	78
5 years	0.00	3.73 [2.25, 6.16]	2.8e-7	45
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_NONISCHCARDMYOP_STRICT – Nonischemic cardiomyopathy
GWS hits: 1

Survival analyses between endpoints

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Plot

before Nonischemic cardiomyopathy
after Nonischemic cardiomyopathy

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Nonischemic cardiomyopathy

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