All-cause Heart Failure

I9_HEARTFAIL_ALLCAUSE

congestive heart failure: Failure of the heart to pump a sufficient amount of blood to meet the needs of the body tissues, resulting in tissue congestion and edema. Signs and symptoms include shortness of breath, pitting edema, enlarged tender liver, engorged neck veins, and pulmonary rales.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions

not I9_HYPERTROCARDMYOP

320463

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

20001

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I9_HEARTFAIL_ALLCAUSE

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 19350 7304 12046
Unadjusted prevalence (%) 6.27 4.21 8.92
Mean age at first event (years) 68.84 69.28 68.57

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_HEARTFAIL_ALLCAUSE – All-cause Heart Failure
GWS hits: 3

Survival analyses between endpoints

Plot

before All-cause Heart Failure
after All-cause Heart Failure

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after All-cause Heart Failure