Endocarditis

I9_ENDOCARD

endocarditis: Inflammation of the endocardium.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 I33, I38, I39*
Hospital discharge: ICD-9 421|4249|0932A
Hospital discharge: ICD-8 421
Cause of death: ICD-10 I33, I38, I39*
Cause of death: ICD-9 421|4249|0932A
Cause of death: ICD-8 421

745

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

733

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Check minimum number of events None

733

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Include endpoints None

733

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I9_ENDOCARD

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF6

Summary Statistics

Key figures

All Female Male
Number of individuals 700 216 484
Unadjusted prevalence (%) 0.23 0.12 0.36
Mean age at first event (years) 58.41 55.65 59.64

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 7.55 [3.06, 18.63] 1.2e-5 182
15 years 0.02 2.89 [1.42, 5.87] 3.3e-3 48
5 years 0.01 8.53 [5.44, 13.35] 7.9e-21 53
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_ENDOCARD – Endocarditis
GWS hits: 0

Survival analyses between endpoints

Plot

before Endocarditis
after Endocarditis

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