Coronary artery bypass grafting

I9_CABG

Coronary Vasospasm: Sudden coronary artery smooth muscle contraction leading to lumen constriction and decreased blood flow.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Operations: NOMESCO codes ^FNA|^FNB|^FNC|^FND|^FNE
Operations: Finnish Hospital League codes ^5311$|^5312$|^5313$|^5314$|^5315$
Operations: Heart Patient codes v1 ^11$|^25$|^111$|^112$|^113$|^119$
Operations: Heart Patient codes v2 ^AA1|^AA2|^AA3|^AAX

63913

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Check pre-conditions, main-only, mode, ICD version None

8962

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Check minimum number of events None

8962

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Include endpoints None

8962

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I9_CABG

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 8693 1502 7191
Unadjusted prevalence (%) 2.82 0.87 5.33
Mean age at first event (years) 64.23 66.45 63.77

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.95 [1.64, 2.31] 1.8e-14 2708
15 years 0.01 1.50 [1.31, 1.73] 7.0e-9 1519
5 years 0.00 1.80 [1.58, 2.04] 4.8e-19 510
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_CABG – Coronary artery bypass grafting
GWS hits: 35

Survival analyses between endpoints

Plot

before Coronary artery bypass grafting
after Coronary artery bypass grafting

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Drugs most likely to be purchased after Coronary artery bypass grafting