Felty syndrome

FELTY

Felty's syndrome: Felty syndrome (FS), also known as ''super rheumatoid'' disease, is a severe form of rheumatoid arthritis (RA), characterized by a triad of RA, splenomegaly and neutropenia, resulting in susceptibility to bacterial infections.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M05.0

Hospital discharge: ICD-9 7141

Hospital discharge: ICD-8 71210

Cause of death: ICD-10 M05.0

Cause of death: ICD-9 7141

Cause of death: ICD-8 71210

131

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

126

Check minimum number of events None

126

Include endpoints None

126

FELTY

Extra metadata

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M05

Name in latin Syndroma Felty

Similar endpoints

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List of similar endpoints to Felty syndrome based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	123	87	36
Unadjusted prevalence (%)	0.04	0.05	0.03
Mean age at first event (years)	59.08	58.78	59.80

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: FELTY – Felty syndrome
GWS hits: 0

Survival analyses between endpoints

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Plot

before Felty syndrome
after Felty syndrome

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Felty syndrome

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